It is only quite recently that medical researchers have identified and described a new group of rare, inherited conditions known as Cryopyrin-Associated Periodic Syndromes or CAPS. CAPS is made up of three disorders that share a number of common symptoms, including recurrent fever/chills, rash, joint pain, fatigue, and eye pain/redness.
These disorders are known as Familial Cold Auto-inflammatory Syndrome (FCAS), Muckle-Wells Syndrome (MWS), and Neonatal-Onset Multisystem
Inflammatory Disease (NOMID). LEARN MORE
FCAS
FCAS is a rare inflammatory disorder characterized by frequent attacks of fever/chills, fatigue, and eye pain/ redness associated with joint pain
and rash triggered by exposure to cooling temperatures. Onset of FCAS occurs during infancy and early childhood and persists throughout the
patient's life.
MWS
MWS is a form of CAPS characterized by recurrent rash, fever/chills, joint pain, fatigue, and eye pain/redness. MWS symptoms are triggered by
random unknown factors and possibly by exercise, stress, or cold. MWS is often associated with hearing loss and/or amyloidosis (deposition of
a protein in organs such as the kidney, which can interfere with organ function.).
NOMID
NOMID, also known as Chronic Infantile Neurologic Cutaneous Articular Syndrome (CINCA), is a rare, congenital, systemic, inflammatory condition
distinguished by recurrent fever, joint disease, rash, and significant central nervous system (CNS) disease. Symptoms of NOMID generally appear
shortly after birth. NOMID is the most severe form of CAPS.